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Medicine that have an effect on liver metabolism can result in elevated blood amounts of codeine. Do not give along with expectorants, Because the more reproduced mucus can't be coughed off due to the antitussive influence of dihydrocodeine.
Little ones with obstructive rest apnea that are addressed with codeine for write-up-tonsillectomy and/or adenoidectomy soreness could be significantly sensitive to its respiratory depressant impact; as a result of possibility of daily life-threatening respiratory depression and death: codeine is contraindicated in all small children more youthful than twelve years of age; It is usually contraindicated for put up-operative administration in pediatric individuals more youthful than 18 several years of age following tonsillectomy and/or adenoidectomy
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Should you pass up a dose, choose it when you don't forget. If it is nearly time for more info the subsequent dose, skip the skipped dose and only acquire the following dose. Don't choose double or more doses.
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The codeine may perhaps maximize frequency of seizures in sufferers with seizure Problems, and may increase hazard of seizures transpiring in other medical settings associated with seizures; keep an eye on individuals which has a historical past of seizure Ailments for worsened seizure Management all through therapy
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Reserve concomitant prescribing of those drugs in individuals for whom other therapy options are insufficient. Limit dosages and durations for the minimal required. Watch intently for signs of respiratory melancholy and sedation.